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Updated: 1 hour 42 min ago

Banner, Scottsdale Healthcare offer new heart valve

Wed, 11/16/2011 - 12:33
Banner Health and Scottsdale Healthcare are among the first in the nation to offer a new artificial heart valve that was just approved by the U.S. Food and Drug Administration. The Sapien Transcatheter Heart Valve can replace a diseased aortic valve without open-heart surgery that previously was required, said Dr. Maulik Shah, director of the cardiac catheterization lab at Scottsdale Healthcare Osborn Medical Center. This new procedure will be an option for patients who are not eligible for open-heart surgery and usually ended up dying, he said... (Source: bizjournals.com Health Care:Physician Practices headlines)
Categories: Publications

Doris Shearman: First to undergo keyhole heart surgery which could save hundreds

Wed, 11/16/2011 - 12:22
Doris Shearman, 80, from South Wales, was too weak to undergo open heart surgery, so doctors used a new, less invasive way of replacing her artificial valve which was worn out. (Source: the Mail online | Health)
Categories: Publications

Efficacy and Safety of Low-Dose Cyclosporine with Everolimus and Steroids in de novo Heart Transplant Patients: A Multicentre, Randomized Trial

Wed, 11/16/2011 - 11:13
A six-month, multicenter, randomized, open-label study was undertaken to determine whether renal function is improved using reduced-exposure cyclosporine (CsA) versus standard-exposure CsA in 199 de novo heart transplant patients receiving everolimus and steroids ± induction therapy. Mean C2 levels were at the low end of the target range in standard-exposure patients (n=100) and exceeded target range in reduced-exposure patients (n=99) throughout the study. Mean serum creatinine at Month 6 (the primary endpoint) was 141.0±53.1 μmol/L in standard-exposure patients versus 130.1±53.7 μmol/L in reduced-exposure patients (P=0.093). The incidence of biopsy-proven acute rejection ≥3A at Month 6 was 21.0% (21/100) in the standard-exposure...
Categories: Publications

Giant cell myocarditis: an unusual presentation

Wed, 11/16/2011 - 04:00
Giant cell myocarditis is a rare but often devastating disease affecting young, otherwise healthy individuals. Patients often die of heart failure and ventricular arrhythmia unless cardiac transplantation is performed. Cardiac magnetic resonance imaging with or without cardiac biopsy can be helpful in making the correct diagnosis and ensuring that correct timely treatment is administered. (Source: Europace)

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Categories: Publications

AHA: Afib Stroke Risk Follows Heart Transplant (CME/CE)

Tue, 11/15/2011 - 22:51
ORLANDO (MedPage Today) -- Atrial fibrillation was present in a significant portion of perioperative heart transplant patients and correlated with a higher complication rate including stroke, according to a single-center study. (Source: MedPage Today Cardiovascular)
Categories: Publications

Effects of Exercise Training in Heart Transplant Recipients: A Meta-Analysis

Tue, 11/15/2011 - 22:00
Cardiology 2011;120:27–35 (DOI:10.1159/000332998) (Source: Cardiology)
Categories: Publications

Racial, Gender Disparities Among Pediatric Heart Transplant Patients Alive 10 Years After Surgery

Tue, 11/15/2011 - 10:00
White heart transplant patients under the age of 18 are more than twice as likely to be alive a decade after surgery as their African-American counterparts, new Johns Hopkins research suggests. The findings, part of a large-scale review of factors that appear to significantly influence long-term survival among pediatric heart transplant patients, are being presented this week at the American Heart Association's annual Scientific Sessions in Orlando... (Source: Health News from Medical News Today)
Categories: Publications

Death Can Be Prevented In People With Arrhythmias Using A Wearable Defibrillator

Tue, 11/15/2011 - 07:00
A wearable defibrillator can prevent sudden death in people with dangerous heart arrhythmias, according to research presented at the American Heart Association's Scientific Sessions 2011. Wearable cardioverter defibrillators are used by people who may be at higher risk for sudden cardiac arrest, including those with weakened heart function, awaiting cardiac transplant or with a condition that prevents or delays them from receiving an implanted defibrillator... (Source: Health News from Medical News Today)
Categories: Publications

Who Needs an RVAD in Addition to an LVAD?

Mon, 10/03/2011 - 03:00
Mechanical circulatory support using left ventricular assist devices (LVAD) has become an accepted mode of therapy for both bridging patients with end-stage heart failure to transplant and as a destination therapy. Right ventricular (RV) dysfunction is common after LVAD insertion and is a significant source of morbidity and mortality in patients undergoing LVAD placement. Several studies have identified clinical, laboratory, hemodynamic, and echocardiographic parameters that may serve as risk factors for RV dysfunction after LVAD placement. Furthermore, scoring systems have been established to help quantitatively predict the potential need for RV support after LVAD placement. (Source: Cardiology Clinics)
Categories: Publications

Toward Total Implantability Using Free-Range Resonant Electrical Energy Delivery System: Achieving Untethered Ventricular Assist Device Operation Over Large Distances

Mon, 10/03/2011 - 03:00
Heart failure is a terminal disease with a very poor prognosis. Although the gold standard of treatment remains heart transplant, only a minority of patients can benefit from transplants. Another promising alternative is mechanical circulatory assistance using ventricular assist devices. The authors envision a completely implantable cardiac assist system affording tether-free mobility in an unrestricted space powered wirelessly by the innovative Free-Range Resonant Electrical Energy Device (FREE-D) system. Patients will have no power drivelines traversing the skin, and this system will allow power to be delivered over room distances and will eliminate trouble-prone wirings, bulky consoles, and replaceable batteries. (Source: Cardiology Clinics)
Categories: Publications

Long-term follow-up of cardiac resynchronization therapy: mechanical resynchronization and reverse left ventricular remodeling are predictive for long-term transplant-free survival

Sat, 10/01/2011 - 05:43
Abstract  We sought to determine whether correction of mechanical left ventricular (LV) dyssynchrony as defined by tissue Doppler imaging (TDI) is predictive for transplant-free long-term survival in patients (pts.) undergoing cardiac resynchronization therapy (CRT). In 76 CRT recipients TDI curves from the septal, lateral, anterior, and inferior basal LV were obtained at baseline and after 6 Â± 4 months. A time difference between regional electromechanical delays (EMD) of ≥40 ms was considered dyssynchronous. At follow-up, pts. were classified as TDI-responders (TDI-R: dyssynchrony at baseline, corrected by CRT) versus non-responders (TDI-NR: either not dyssynchronous at baseline, or persisting dyssynchrony). Pts. were then followed by standard echocar...
Categories: Publications

Cardiac risk assessment for renal transplantation. are patients being managed appropriately in our hospital?

Sat, 10/01/2011 - 03:00
Introduction: Cardiovascular (CV) disease remains a leading cause of post-renal transplantation morbidity and mortality. Currently, there is little consensus regarding both cardiovascular screening and management of coronary artery disease (CAD) prior to renal transplantation. (Source: Atherosclerosis)

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Categories: Publications

A lempel-ziv complexity-based neural network pruning algorithm.

Sat, 10/01/2011 - 03:00
Authors: Ahmed SU, Shahjahan M, Murase K Abstract This paper presents a pruning method for artificial neural networks (ANNs) based on the 'Lempel-Ziv complexity' (LZC) measure. We call this method the 'silent pruning algorithm' (SPA). The term 'silent' is used in the sense that SPA prunes ANNs without causing much disturbance during the network training. SPA prunes hidden units during the training process according to their ranks computed from LZC. LZC extracts the number of unique patterns in a time sequence obtained from the output of a hidden unit and a smaller value of LZC indicates higher redundancy of a hidden unit. SPA has a great resemblance to biological brains since it encourages higher complexity during the training process. SPA is similar to, yet different from, existin...
Categories: Publications

Yellow fever vaccination in organ transplanted patients: is it safe? A multicenter study

Sat, 10/01/2011 - 03:00
ConclusionsYFV showed no important side effects in this cohort of solid organ transplanted patients. However, owing to the small number of studied patients, it is not possible to extend these findings to the rest of the transplanted population, assuring safety. Therefore, these data are not strong enough to safely recommend YFV in organ transplanted recipients, as severe, even life‐threatening side effects may occur. (Source: Transplant Infectious Disease)
Categories: Publications

10th Congress of the Polish Transplantation Society (PTT)

Sat, 10/01/2011 - 03:00
The 10th Congress of the Polish Transplantation Society (PTT) was held in Ossa near Warsaw on June 9–11, 2011. Almost 550 participants attended the Congress. The scientific program consisted of plenary session with eight state-of-the-art lectures presented by invited international speakers: Kathryn Wood (UK), Barry Kahan (USA), Henrik Ekberg (Sweden), Ondrej Viklicky & Stefan Vitko (Czech Republik), Teun van Gelder (the Netherlands), Wojciech Rowiński (Poland), and Mirosław Smogorzewski (USA). Several sessions on progress in kidney, liver, heart and lungs, pancreas and islets, hematopoietic cells, biostatics, and cornea transplantation were conducted. Special sessions for coordinators and nurses were organized. The opening lecture was delivered by Prof. Maria Siemionow. (Source: Transp...
Categories: Publications

Fifty Years in the Vineyard of Transplantation: Looking Back

Sat, 10/01/2011 - 03:00
Abstract: The past 5 decades have documented remarkable advances in basic knowledge and clinical expertise in transplantation. The first 12 years of this half century of my participation in the enterprise were consumed with the isolation, chemical characterization, and application of histocompatibility antigens purified from mouse, guinea pig, and human tissues, demonstrating that their specificity was based on unique amino acid sequences in protein structures. Initial unsuccessful attempts to use native molecules to induce tolerance in rat renal or heart transplantation models were followed by limited success when they were administered with a brief perioperative course of cyclosporine (CsA). Production of allochimeric constructs of class I major histocompatibility complex molecules beari...
Categories: Publications

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