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Genetic factors control regenerative properties of blood-forming stem cells, UCLA studies show

Mon, 12/05/2016 - 15:00
FINDINGSResearchers from the UCLA Department of Medicine, Division of Hematology Oncology and the  Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have published two studies that define how key genetic factors affect blood-forming stem cells by either accelerating or hindering the cells ’ regenerative properties. The findings could one day lead to improved treatments for people undergoing common therapies for cancer such as chemotherapy and radiation. BACKGROUNDBlood-forming stem cells, or hematopoietic stem cells, are found in the bone marrow. These cells have two unique properties: They can self-renew and, through a process called differentiation, they can form any type of blood cell. A healthy immune system depends on the regenerative abilities of...
Categories: Publications

Scientists create artificial blood that delivers oxygen to tissues in the body

Mon, 12/05/2016 - 02:43
Dennis Thompson, HealthDay News Scientists created an artificial red blood cell that picks up oxygen in the lungs and takes it to tissues, and may improve trauma victims' chance of survival. (Source: Health News - UPI.com)

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Longer Preservation Time Doesn ' t Harm Lungs for Transplant Longer Preservation Time Doesn ' t Harm Lungs for Transplant

Tue, 11/29/2016 - 22:14
Extending overall preservation time via ex-vivo lung perfusion (EVLP) appears to have no negative impact on short-term outcomes of lung transplantation, according to Canadian and Swiss investigators.Reuters Health Information (Source: Medscape Transplantation Headlines)
Categories: Publications

Cold-Warm-Cold Lung Preservation Extends Transplant Window (CME/CE)

Sun, 11/20/2016 - 23:35
(MedPage Today) -- Harvested lungs kept viable up to 21 hours (Source: MedPage Today Pulmonary)
Categories: Publications

New technique keeps donor lungs viable longer: Study

Fri, 11/18/2016 - 18:56
HealthDay News A technique that allows lungs destined for transplants to be preserved longer works well, a new Canadian study finds. (Source: Health News - UPI.com)
Categories: Publications

New Technique Keeps Donor Lungs Viable Longer

Fri, 11/18/2016 - 16:00
Strategy allows doctors more time to assess organs, transport for transplant Source: HealthDay Related MedlinePlus Page: Lung Transplantation (Source: MedlinePlus Health News)
Categories: Publications

New Technique Keeps Donor Lungs Viable Longer: Study

Fri, 11/18/2016 - 11:11
FRIDAY, Nov. 18, 2016 -- A technique that allows lungs destined for transplants to be preserved longer works well, a new Canadian study finds. The strategy, called ex-vivo lung perfusion (EVLP), allows preservation of lungs for up to 12 hours,... (Source: Drugs.com - Daily MedNews)

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Preserving donor lungs longer makes transplant more elective than emergency surgery

Thu, 11/17/2016 - 04:00
(University Health Network) A new method which doubles the usual time donor lungs can remain outside the body can benefit patients, staff and allow retrieval of donor lungs across greater geographical areas. (Source: EurekAlert! - Medicine and Health)
Categories: Publications

Can artery 'banks' transform vascular medicine?

Tue, 11/15/2016 - 04:00
(Morgridge Institute for Research) The Morgridge Institute for Research and the University of Wisconsin-Madison will address both the engineering and biomedical hurdles involved in creating stem cell-derived arteries for transplant as part of a five-year, $8 million project funded by the National Heart, Lung and Blood Institute (NHLBI). (Source: EurekAlert! - Medicine and Health)
Categories: Publications

How To Boost Melatonin Naturally

Thu, 11/10/2016 - 20:18
Most people know melatonin as the sleep hormone. And that’s right. It helps your body cycle down every night so you can rest. But melatonin is so much more than that… It’s also one of your body’s most powerful cancer killers. Studies show melatonin boosts the immune system. It protects against the toxic side effects of chemo and radiation. It improves wound healing after surgery. And it even increases cancer survival rates.1 And new research proves that melatonin suppresses the growth of breast cancer tumors. How does melatonin affect breast cancer? Mammograms detect cancer. In a lab at Michigan State University, researchers grew breast cancer tumors called “mammospheres.” They fed the tumors with chemicals that we already know fuel growth. They used re...
Categories: Publications

Meet The Doctor Behind The Most Extreme Face Transplant Ever

Tue, 11/01/2016 - 17:15
function onPlayerReadyVidible(e){'undefined'!=typeof HPTrack&&HPTrack.Vid.Vidible_track(e)}!function(e,i){if(e.vdb_Player){if('object'==typeof commercial_video){var a='',o='m.fwsitesection='+commercial_video.site_and_category;if(a+=o,commercial_video['package']){var c='&m.fwkeyvalues=sponsorship%3D'+commercial_video['package'];a+=c}e.setAttribute('vdb_params',a)}i(e.vdb_Player)}else{var t=arguments.callee;setTimeout(function(){t(e,i)},0)}}(document.getElementById('vidible_1'),onPlayerReadyVidible); Last August, Dr. Eduardo Rodriguez performed the most extensive face transplant operation ever.  In the 26-hour operation, which took place at New York University Langone Medical Center, the dentist-turned-plastic-surgeon and his team removed the face and scalp of a young victim of ...

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Organovo unveils bioprinted liver transplant patches

Wed, 10/05/2016 - 22:16
Organovo (PINK:ONVO) today announced it is developing 3D bioprinted human liver tissue designed for direct transplantation to patients. The move to human development comes based on “strong results” from preclinical animal model studies, the San Diego, Calif.-based company said. The company expects to pursue a formal preclinical development program. “We’re excited to introduce an implantable bioprinted liver tissue as the first preclinical candidate in our therapeutic tissue portfolio, and see the early results as extremely promising. The scientific and commercial progress we have already made with ExVive Human Liver Tissue in drug toxicity testing has given us a firm foundation upon which to build a larger tissue for transplant.  Advancing our first therapeutic tissu...
Categories: Publications

UCLA lung transplant program performs landmark 1000th surgery

Tue, 10/04/2016 - 08:03
TheUCLA Lung Transplant program performed its 1,000th transplant surgery in mid-September, becoming the first program on the West Coast, and one of only seven centers nationwide, to achieve this milestone.The recipient of the donor lungs was Elba De Contreras, 59, from Goleta, California, who suffered from idiopathic pulmonary fibrosis and pulmonary hypertension. The six-hour surgery took place at Ronald Reagan UCLA Medical Center, led by Dr. Abbas Ardehali, surgical director of the lung and heart transplant programs.De Contreras, who relied on an oxygen tank prior to her surgery, is recuperating well and said she feels happy and energetic. With three sons and four grandkids, De Contreras said she looks forward to resuming her social life. Her husband, Willy, said that the donor lungs have...
Categories: Publications

UCLA lung transplant program performs landmark 1,000th surgery

Mon, 10/03/2016 - 23:24
TheUCLA Lung Transplant program performed its 1,000th transplant surgery in mid-September, becoming the first program on the West Coast, and one of only seven centers nationwide, to achieve this milestone.The recipient of the donor lungs was Elba De Contreras, 59, from Goleta, California, who suffered from idiopathic pulmonary fibrosis and pulmonary hypertension. The six-hour surgery took place at Ronald Reagan UCLA Medical Center, led by Dr. Abbas Ardehali, surgical director of the lung and heart transplant programs.De Contreras, who relied on an oxygen tank prior to her surgery, is recuperating well and said she feels happy and energetic. With three sons and four grandkids, De Contreras said she looks forward to resuming her social life. Her husband, Willy, said that the donor lungs have...
Categories: Publications

An Intervention for Self-Management After Lung Transplant An Intervention for Self-Management After Lung Transplant

Mon, 10/03/2016 - 03:38
Could this novel intervention help improve self-management behaviors among lung transplant recipients?American Journal of Transplantation (Source: Medscape Transplantation Headlines)

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Katie Prager dies days after her husband

Fri, 09/23/2016 - 21:05
Katie Prager, the wife in the real "Fault in Our Stars" couple, died Thursday after complications from cystic fibrosis and a lung transplant. She was 26 years old. (Source: CNN.com - Health)
Categories: Publications

Katie Prager, wife in real 'Fault in Our Stars' couple, dies

Fri, 09/23/2016 - 15:21
Katie Prager, the wife in the real "Fault in Our Stars" couple, died Thursday after complications from cystic fibrosis and a lung transplant. She was 26 years old. (Source: CNN.com - Health)
Categories: Publications

Real 'Fault in Our Stars' couple: Katie Prager dies

Thu, 09/22/2016 - 20:42
Katie Prager, the wife in the real "Fault in Our Stars" couple, died Thursday after complications from cystic fibrosis and a lung transplant. She was 26 years old. (Source: CNN.com - Health)
Categories: Publications

'Fault in our Stars' wife dies 5 days after husband

Thu, 09/22/2016 - 20:30
Katie Prager died after complications from cystic fibrosis and a lung transplant. She was 26 years old. (Source: CNN.com - Health)
Categories: Publications

Contraceptive pills not proven to protect against the flu

Mon, 09/19/2016 - 15:30
Conclusion These are interesting scientific findings but they have limited implications. Animal studies are useful for giving an indication of how biological processes may work in humans but we're not identical. Then the scenarios tested here – the progesterone, or the flu injection – can be taken as representative of real-life in humans. For one thing all the mice had surgery to remove their ovaries before being infected. It makes sense that the mice that had been given some additional recovery boost in the form of hormone replacement may have been in a better health state than those left hormone depleted. They were also directly inoculated through the nose with a flu dose that has previously been demonstrated to be lethal in these animals, and the animals did die. It's just those ...

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