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Bayesian Probit Regression Model for the Diagnosis of Pulmonary Fibrosis: Proof-of-Principle.

Wed, 10/05/2011 - 03:00
Conclusions: This study represents the first use of BPR on whole lung tissue; previously, BPR was primarily used to develop predictive models for cancer. This also represents the first report of an independently validated IPF gene expression signature. In summary, BPR is a promising tool for the development of gene expression signatures from non-neoplastic lung tissue. In the future, BPR might be used to develop definitive diagnostic gene signatures for IPF, prognostic gene signatures for IPF or gene signatures for other non-neoplastic lung disorders such as bronchiolitis obliterans. (Source: BMC Medical Genomics)
Categories: Publications

Combining tricuspid valve repair with double lung transplantation in patients with severe pulmonary hypertension, tricuspid regurgitation, and right ventricular dysfunction.

Sat, 10/01/2011 - 03:00
CONCLUSIONS: Combined TVR and DLTx procedures were successfully performed without an increase in morbidity or mortality and contributed to decreased primary graft dysfunction. In our experience, this combined operative approach achieves clinical outcomes equal or superior to the outcomes seen in DLTx patients without RV dysfunction and severe tricuspid regurgitation. PMID: 21700686 [PubMed - in process] (Source: Chest)

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Categories: Publications

CD40 Ligand Deficiency With Grade III Liver Fibrosis, Transplanted by a Treosulphan-based Conditioning Regimen.

Sat, 10/01/2011 - 03:00
In conclusion, treosulphan is a new agent for conditioning regimen with less toxicity in patients with severe liver disease. PMID: 21967264 [PubMed - in process] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Categories: Publications

10th Congress of the Polish Transplantation Society (PTT)

Sat, 10/01/2011 - 03:00
The 10th Congress of the Polish Transplantation Society (PTT) was held in Ossa near Warsaw on June 9–11, 2011. Almost 550 participants attended the Congress. The scientific program consisted of plenary session with eight state-of-the-art lectures presented by invited international speakers: Kathryn Wood (UK), Barry Kahan (USA), Henrik Ekberg (Sweden), Ondrej Viklicky & Stefan Vitko (Czech Republik), Teun van Gelder (the Netherlands), Wojciech Rowiński (Poland), and Mirosław Smogorzewski (USA). Several sessions on progress in kidney, liver, heart and lungs, pancreas and islets, hematopoietic cells, biostatics, and cornea transplantation were conducted. Special sessions for coordinators and nurses were organized. The opening lecture was delivered by Prof. Maria Siemionow. (Source: Transp...
Categories: Publications

Lymphocyte Subtypes CD3+, CD19+, CD16+CD56+, CD4+, CD8+, and CD3+HLA-DR+ in Peripheral Blood Obtained From Patients After Thoracic Organ Transplantation

Sat, 10/01/2011 - 03:00
Conclusion: A clear tendency to a decrease number of peripheral blood lymphocytes of various subtypes was observed among thoracic organ recipients in the first year posttransplantation with the exception of activated HLA-DR+ cells. After the first year, there was slow restoration of lymphocytes. (Source: Transplantation Proceedings)
Categories: Publications

Procalcitonin Serum Concentration in Lung Transplant Recipients During Mold Colonization or Infection

Sat, 10/01/2011 - 03:00
Conclusions: The mold colonization of transplanted lung is a frequent complication and should be considered even in the case of proper prophylaxis. Procalcitonin might be the marker helpful in mold infection diagnosis. (Source: Transplantation Proceedings)
Categories: Publications

The protective role of laparoscopic antireflux surgery against aspiration of pepsin after lung transplantation

Sat, 10/01/2011 - 03:00
Conclusion: This study compared pepsin in the BALF from lung transplant patients with and without LARS. Our data show that: (1) the detection of pepsin in the BALF proves aspiration because it is not present in healthy volunteers, and (2) LARS appears effective as a measure to prevent the aspiration of gastroesophageal refluxate in the lung transplant population. We believe that these findings provide a mechanism for those studies suggesting that LARS may prevent nonallogenic injury to the transplanted lungs from aspiration of gastroesophageal contents. (Source: Surgery)

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Categories: Publications

Donation after cardiac death: A 29-year experience

Sat, 10/01/2011 - 03:00
Conclusion: This series represents the largest single center experience with more than 1000 DCD transplants and given the critical demand for organs, demonstrates successful kidney, pancreas, liver, and lung allografts from DCD donors. (Source: Surgery)
Categories: Publications

A novel computer-aided lung nodule detection system for CT images.

Sat, 10/01/2011 - 03:00
Conclusions: A complete CAD system incorporating novel features is presented, and its performance with three separate classifiers is compared and analyzed. The overall performance of our CAD system equipped with any of the three classifiers is well with respect to other methods described in literature. PMID: 21992380 [PubMed - in process] (Source: Medical Physics)
Categories: Publications

Scientific Registry of the International Society for Heart and Lung Transplantation: Introduction to The 2011 Annual Reports

Fri, 09/30/2011 - 22:46
We enthusiastically present the 2011 Annual Reports of the Scientific Registry (the Registry) of the International Society for Heart and Lung Transplantation (ISHLT). The Registry has now collected, analyzed, and reported data for more than 142,000 heart, heart-lung, and lung transplants. We are delighted to announce a new reporting relationship with L'agence de la Biomédicine, which allows us, for the first time, to add to the Registry data related to more than 13,000 heart, heart-lung, and lung transplants performed in France between April 1968 and December 2009. The addition of the French data, in combination with continued participation of more than 200 other centers worldwide (), has resulted in the past year being our most active to date (). (Source: The Journal of Heart and Lung Tr...
Categories: Publications

The Registry of the International Society for Heart and Lung Transplantation: Twenty-eighth Adult Heart Transplant Report—2011

Fri, 09/30/2011 - 22:46
This Twenty-eighth Report of the International Society for Heart and Lung Transplantation (ISHLT) Transplant Registry is based on data submitted by participating transplant centers worldwide. A total of 388 heart transplant centers have contributed information to the Registry. This year we have also achieved another important milestone: the 100,000th heart transplant recipient was registered in the database. (Source: The Journal of Heart and Lung Transplantation)
Categories: Publications

The Registry of the International Society for Heart and Lung Transplantation: Fourteenth Pediatric Heart Transplantation Report—2011

Fri, 09/30/2011 - 22:46
The first pediatric heart transplantation was performed in 1968. Since then, nearly 10,000 transplants in children have been reported. This 14th Pediatric Heart Transplantation Report continues to document the evolving management of pediatric transplant recipients and their outcomes. (Source: The Journal of Heart and Lung Transplantation)

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Categories: Publications

The Registry of the International Society for Heart and Lung Transplantation: Twenty-eighth Adult Lung and Heart-Lung Transplant Report—2011

Fri, 09/30/2011 - 22:46
The Registry of the International Society for Heart and Lung Transplantation (ISHLT) has documented trends in clinical lung and heart-lung transplantation since the inception of these procedures. Detailed heart-lung transplantation data have been included in the Registry annual reports since 1984 and lung transplantation data since 1989. Through June 30, 2010, the Registry contains data on 4,248 heart-lung and 38,119 lung transplants from centers around the world. This 28th Lung and Heart-Lung Registry Report summarizes the current status of lung and heart-lung transplantation by reporting data on this international group of patients, focusing on adults. More detailed information is presented in the full set of more than 200 slides that can be found on the ISHLT Web site at www.ishlt.org/r...
Categories: Publications

The Registry of the International Society for Heart and Lung Transplantation: Fourteenth Pediatric Lung and Heart-Lung Transplantation Report—2011

Fri, 09/30/2011 - 22:46
This Fourteenth Pediatric Lung and Heart-Lung Transplantation Report covers the pediatric lung transplantation and heart-lung transplantation experience from January 1986 through June 2010. During this period, 1,664 pediatric lung transplant procedures and 653 pediatric heart-lung transplant procedures were reported to the International Society for Heart and Lung Transplantation (ISHLT) Registry. It is important to note that recent figures include pediatric lung and heart-lung transplant procedures dating back to 1987 that were previously not reported to the ISHLT Registry but were retrospectively entered in 2010. In 2009, the last complete year included in this year's ISHLT Registry report, 127 pediatric lung transplant procedures were reported, which is an increase of 43% compared with 2...
Categories: Publications

Antioxidant properties of pioglitazone limit nicotinamide adenine dinucleotide phosphate hydrogen oxidase and augment superoxide dismutase activity in cardiac allotransplantation

Fri, 09/30/2011 - 22:46
Conclusions: Pioglitazone can suppress the oxidative stress and damage and can stimulate antioxidant capacity in cardiac allografts after transplantation. Mitigation of graft oxidant stress could be an important mechanism through which pioglitazone confers benefit after cardiac transplantation. (Source: The Journal of Heart and Lung Transplantation)
Categories: Publications

Early vitamin C and E supplementation and cardiac allograft vasculopathy: 10-Year follow-up from a randomized, controlled study

Fri, 09/30/2011 - 22:46
Cardiac allograft vasculopathy (CAV) limits the long-term success and survival after heart transplantation, and new therapies are needed. From 1996 to 1998, we conducted a randomized trial of vitamins C and E in 40 patients post-transplant, and assessed CAV progression by intravascular ultrasound (IVUS). After 1 year of treatment, patients assigned to vitamins showed a significantly smaller change in intimal index compared with placebo. No clinical end-points were tested. Based on these data, we began routine vitamin supplementation for most patients. Herein we present 10-year follow-up data according to initial randomization to identify long-term clinical benefit. (Source: The Journal of Heart and Lung Transplantation)
Categories: Publications

Erratum

Fri, 09/30/2011 - 22:46
Schuurmans MM, Tini GM, Dalar L, Fretz G, Benden C, Boehler A. Pandemic 2009 H1N1 influenza virus vaccination in lung transplant recipients: coverage, safety and clinical effectiveness in the Zurich cohort. J Heart Lung Transplant 2011 Jun;30(6):685–90. (Source: The Journal of Heart and Lung Transplantation)

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Categories: Publications

Editorial Board

Fri, 09/30/2011 - 22:46
(Source: The Journal of Heart and Lung Transplantation)
Categories: Publications

Contents

Fri, 09/30/2011 - 22:46
(Source: The Journal of Heart and Lung Transplantation)
Categories: Publications

Lung Transplantation Resumes At Alfred hospital

Fri, 09/30/2011 - 14:27
(Source: Cystic Fibrosis Worldwide)
Categories: Publications

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